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Cancer Gene Therapy Vaccines
Data on cancer gene therapy vaccines described by researchers at University of Sao Paulo, Heart Institute
June 30th, 2009
Investigators publish new data in the report 'Immune response to vaccination with DNA-Hsp65 in a phase I clinical trial with head and neck cancer patients.' "DNA-hsp65, a DNA vaccine encoding the 65-kDa heat-shock protein of Mycobacterium leprae (Hsp65) is capable of inducing the reduction of established tumors in mouse models. We conducted a phase I clinical trial of DNA-hsp65 in patients with advanced head and neck carcinoma," scientists in Sao Paulo, Brazil report. "In this article, we report on the vaccine's potential to induce immune responses to Hsp65 and to its human homologue, Hsp60, in these patients. Twenty-one patients with unresectable squamous cell...
Source: Cancer Weekly (2009-06-30)
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