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Gene Therapy
Researchers from Shanghai Institute of Applied Physics report on findings in gene therapy
June 30th, 2009
Researchers detail in 'M-PEIs nanogels: potential nonviral vector for systemic plasmid delivery to tumor cells,' new data in gene therapy. "Successfully systemic gene therapy has been hindered by vector-related limitations, including toxicity and inefficient gene delivery to tumor cells after intravenous administration. In this study, we evaluated the potential of spherical polyethylenimine nanogels (M-PEIs) as a novel vector for intravenous delivery of plasmids to tumor cells," scientists in Shanghai, People's Republic of China report. "M-PEIs provided a sustained release of plasmids up to 14 days and were also effective in protecting plasmids from enzymatic...
Source: Cancer Weekly (2009-06-30)
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