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Cancer Weekly

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Vaccines



Scientists at National Institutes of Health describe research in vaccines



June 30th, 2009

Research findings, 'Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches,' are discussed in a new report. "Dendritic cells (DCs) serve as central regulators of adaptive immunity by presenting antigens and providing necessary co-signals. Environmental information received by the DCs determines the co-signals delivered to the responding adaptive cells and, ultimately, the outcome of the interaction," investigators in the United States report.

"DCs loaded with relevant antigens have been used as therapeutic cellular vaccines, but the optimal antigen loading method has not been determined. We compared...


Source: Cancer Weekly (2009-06-30)

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