Cancer Weekly
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Angiogenesis
New angiogenesis research from Kaohsiung Medical University described
June 30th, 2009
According to recent research from Kaohsiung, Taiwan, "This study examines whether the expression of cyclooxgenase-2 (COX-2) in urothelial carcinoma (UC) is associated with macrophage infiltration, hypoxia-inducible factor-1 alpha (HIF-1 alpha) expression and angiogenesis. We investigated the expression of COX-2 associated with HIF-1 alpha and performed double immunohistochemical analysis of 216 UCs for COX-2 expression and the correlation with tumor-associated- macrophage (TAM) density and microvessel density (MVD) in situ." "A high expression of COX-2 was positively correlated with tumor invasiveness, histologic grade and HIF-1 alpha expression in UC (p <0.0001, p =...
Source: Cancer Weekly (2009-06-30)
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