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Cancer Weekly

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Angiogenesis



Research findings from University of Bari, Medical Department update understanding of angiogenesis



June 30th, 2009

According to a study from Bari, Italy, "In this study we purposed an alternative method to study the angiogenic and invasive potential of neuroblastoma cell suspensions implanted on the chick embryo chorioallantoic membrane (CAM) surface. Neuroblastoma cells were seeded in Matrigel and thereafter the suspension was pipetted onto the CAM surface at day 8 of incubation inside a silicon ring previously loaded onto the CAM surface."

"Four days after implantation, the silicon ring was removed and the angiogenic and invasive response were studied morphologically at macroscopic and microscopic levels and by reverse transcriptase-polymerase chain reaction (RT-PCR) by using...


Source: Cancer Weekly (2009-06-30)

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