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Cancer Weekly

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Basal Cell Cancer



Study data from J.K. Karen and co-authors update knowledge of basal cell cancer



June 30th, 2009

" High-resolution real-time imaging of human skin is possible with a confocal microscope either in vivo or in freshly excised tissue ex vivo. Nuclear and cellular morphology is observed in thin optical sections, similar to that in conventional histology," researchers in the United States report.

"Contrast agents such as acridine orange in fluorescence and acetic acid in reflectance have been used in ex vivo imaging to enhance nuclear contrast. Objectives To evaluate the sensitivity and specificity of ex vivo real-time imaging with fluorescence confocal mosaicing microscopy, using acridine orange, for the detection of residual basal cell carcinoma (BCC) in Mohs fresh...


Source: Cancer Weekly (2009-06-30)

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