Cancer Weekly
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Cancer Vaccines
New cancer vaccines research from Tel-Aviv University, Medical Department described
June 30th, 2009
According to a study from Tel Aviv, Israel, "Indolent B-cell lymphomas are characterized by repeated remissions and relapses with most patients eventually dying of the disease. Although combination treatments with chemotherapy and the anti-CD20 antibody rituximab improved duration of remissions and overall survival, the disease is essentially incurable." "Thus, novel therapeutic approaches are needed. One such approach is active immunization with dendritic cells (DCs). Given that rituximab depletes patients of normal B cells, optimal vaccination strategies for rituximab-treated patients require induction of effector T cells. We have previously demonstrated in a murine...
Source: Cancer Weekly (2009-06-30)
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