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Leukemia Gene Therapy
Data on leukemia gene therapy published by C. Kumar and colleagues
July 7th, 2009
New investigation results, 'Kinase drug discovery approaches in chronic myeloproliferative disorders,' are detailed in a study published in Oncogene. According to a study from the United States, "Myeloproliferative disorders (MPDs) are clonal malignancies that arise from hematopoietic progenitors and characterized by overproduction of mature, functional blood cells. These disorders can be broadly characterized into Philadelphia chromosome-positive (Ph(+)) or negative (Ph(-)) genetic groupings." "Chronic myeloid leukemia (CML) is a Ph(+) MPD that is defined on the basis of its molecular lesion, the BCR-ABL fusion gene. Inhibitors directed at the constitutive...
Source: Cancer Weekly (2009-07-07)
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