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Cancer Weekly

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Acid Reflux Disease



New acid reflux disease study findings recently were published by researchers at Semmelweis University



July 7th, 2009

"Neoplastic progression in Barrett's esophagus (BE) occurs by a multistep process associated with early molecular and morphological changes. This study evaluated cell proliferation and p53 expression and their correlation in the development and progression of esophageal adenocarcinoma," researchers in Budapest, Hungary report.

"PCNA and p53 expressions were analyzed in biopsy samples by immunohistochemistry including patients with reflux esophagitis, BE, BE with concomitant esophagitis, Barrett's dysplasia, esophageal adenocarcinoma and a control group without any histological changes. Progressive increase in cell proliferation and p53 expression was found in the...


Source: Cancer Weekly (2009-07-07)

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