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Carcinoma Genetics

Data from Korea University, Department of Pathology advance knowledge in carcinoma genetics

Published in Cancer Weekly, July 7th, 2009

Investigators publish new data in the report 'Genetic alterations and chemosensitivity profile in newly established human renal collecting duct carcinoma cell lines.' "To determine the genetic alterations and chemosensitivity profile of collecting duct carcinoma (CDC) of the kidney, as it is a rare, highly aggressive malignant tumor with frequent distant metastases. We first established and characterized two human CDC cell lines designated AP3 and AP8, respectively," researchers in Korea report.

"The CDC cell lines were assessed using microarray-based comparative genomic hybridization and chemosensitivity testing. The CDC cells grew in vitro as an adherent monolayer...

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