Enzyme Research

New data from University of Genoa illuminate research in enzyme research

Published in Cancer Weekly, July 14th, 2009

"Molecular signatures of tumors with prognostic and predictive value are now available. However, several technical problems prevent the performing of gene expression profiles in routine diagnostics," scientists writing in the journal Diagnostic Molecular Pathology report.

"The highly sensitive fluorescence-based real-time quantitative reverse transcriptase-polymerase chain reaction procedure is able to analyze mRNA levels from formalin-fixed paraffin-embedded (FFPE) tissues, the most commonly available source of tumor samples with well-documented information. However, the time-dependent fragmentation and small amount of RNA extracted from FFPE requires a...

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Source: Cancer Weekly (2009-07-14)

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