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Cancer Weekly

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Renal Cell Carcinoma



New renal cell carcinoma study findings have been reported by M.M. Baldewijns and colleagues



July 14th, 2009

According to a study from Netherlands, "To assess ongoing lymphangiogenesis in renal cell carcinoma (RCC) by histomorphometry and by quantifying mRNA expression levels of lymphangiogenesis-related factors. Using D2-40 antibody as a lymphatic marker, lymph vessels were counted in tissue sections of 150 clear-cell RCCs (ccRCC) and 61 non-neoplastic controls, using the Chalkley method, which measures the relative lymph vessel area (LVA)."

"Double-staining with Ki67 and D2-40 was used to assess active lymphangiogenesis. In a subset of 25 ccRCCs and nine non-neoplastic controls mRNA expression levels of lymphangiogenic factors were determined by real-time quantitative...


Source: Cancer Weekly (2009-07-14)

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