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Studies from New York University add new findings in the area of life sciences

Published in Cancer Weekly, July 14th, 2009

Fresh data on life sciences are presented in the report 'Alterations of histone modifications by cobalt compounds.' According to recent research published in the journal Carcinogenesis, "In the present study, we examined the effects of CoCl(2) on multiple histone modifications at the global level. We found that in both human lung carcinoma A549 cells and human bronchial epithelial Beas-2B cells, exposure to CoCl(2) (>/=200 muM) for 24 h increased H3K4me3, H3K9me2, H3K9me3, H3K27me3, H3K36me3, uH2A and uH2B but decreased acetylation at histone H4 (AcH4)."

"Further investigation demonstrated that in A549 cells, the increase in H3K4me3 and H3K27me3 by cobalt ions...

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