Life Sciences
Researchers from University of Dresden detail findings in life sciences
Published in Cancer Weekly, July 28th, 2009
In this recently published article, scientists in Dresden, Germany conducted a study "To evaluate the association of germ-line polymorphisms of genes that may impact treatment outcome of platinum and fluorouracil combination chemotherapy in advanced gastric cancer (AGC). Blood samples of 156 patients enrolled onto a phase III study comparing fluorouracil, leucovorin, and oxaliplatin with fluorouracil, leucovorin, and cisplatin were collected."
"Polymorphisms within genes of TS, MTHFR, MTR, OPRT, XPD, ERCC1, XRCC1, XPA, GSTP1, GSTT1, and GSTM1 were genotyped using polymerase chain reaction-based techniques. Median overall survival (OS) was 11.8 months (95% CI, 9.75 to...
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Source: Cancer Weekly (2009-07-28)
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