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Cancer

Reports on cancer findings from R. Mortarini and co-researchers provide new insights

Published in Cancer Weekly, August 4th, 2009

In this recent study, researchers in Milan, Italy conducted a study "To assess the extent of signal transducer and activator of transcription (STAT) activation in response to interleukin 2 (IL-2) in melanoma patients' T cells, along with clinical stage of tumor progression. T lymphocytes from peripheral blood of healthy donors and of American Joint Committee on Cancer stage I to IV melanoma patients, as well as from metastatic lymph nodes of patients, were evaluated for responsiveness to IL-2."

"CFSE assays and single-cell phospho-STAT-specific flow cytometry screening were used. T cells from advanced melanoma patients, in comparison with healthy donors, showed reduced...

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