Cancer

Scientists at Stanford University detail research in cancer

Published in Cancer Weekly, August 4th, 2009

"Immune dysfunction develops in patients with many cancer types and may contribute to tumor progression and failure of immunotherapy. Mechanisms underlying cancer-associated immune dysfunction are not fully understood," scientists writing in the journal Proceedings of the National Academy of Sciences of the United States of America report.

"Efficient IFN signaling is critical to lymphocyte function; animals rendered deficient in IFN signaling develop cancer at higher rates. We hypothesized that altered IFN signaling may be a key mechanism of immune dysfunction common to cancer. To address this, we assessed the functional responses to IFN in peripheral blood...

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Source: Cancer Weekly (2009-08-04)

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