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Study findings from P.D. Palma et al provide new insights into cancer

Published in Cancer Weekly, August 4th, 2009

"The reproducibility of cervical histology diagnoses is critical for efficient screening and to evaluate the effectiveness of new technologies. The vast majority of cervical intraepithelial neoplasia (CIN) diagnoses reported in the New Technologies for Cervical Cancer study were blindly reviewed by 2 independent pathologists," researchers in Rome, Italy report.

"Only H&E-stained slides were used for the review. The reviewers were asked to reclassify cases using the following categories: normal CIN 1, CIN 2, CIN 3, and squamous and glandular invasive cancer. We reviewed 1, 003 cases. The interobserver agreement was 0.36 (95% confidence interval [CI], 0.32-0.40) with an...

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