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Cancer Gene Therapy

Nanjing University publishes research in cancer gene therapy

Published in Cancer Weekly, August 4th, 2009

Research findings, 'Bifidobacterium longum as a delivery system of TRAIL and endostatin cooperates with chemotherapeutic drugs to inhibit hypoxic tumor growth,' are discussed in a new report. According to a study from Nanjing, People's Republic of China, "In our previous study, we have shown that vector pBV22210 containing a chloramphenicol resistance and a cryptic plasmid pMB1 from Bifidobacterium longum strain could stably replicate and did not significantly affect the biological characteristics of B. longum. In this study, B. longum was transfected by electroporation with pBV22210 encoding the extracellular domain of TRAIL (B. longum-pBV22210-TRAIL) and its carbohydrate fermentation and...

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