Cancer Gene Therapy
Researchers from Hokkaido University, Faculty of Pharmaceutical Sciences describe findings in cancer gene therapy
Published in Cancer Weekly, August 4th, 2009
Current study results from the report, 'Trichostatin A with adenovirus-mediated p53 gene transfer synergistically induces apoptosis in breast cancer cell line MDA-MB-231,' have been published. "Although the p53 anti-oncogene is an important target for gene therapy of cancer, some cancers are resistant to p53 gene transfer. For this reason, it is important to find effective drugs to enhance cytotoxic effects of p53 gene transfer," scientists writing in the journal Oncology Reports report.
"Recent reports demonstrated that some histone deacetylase inhibitors in combination with p53 gene therapy induced apoptosis in certain cancer cells more efficiently than p53...
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Source: Cancer Weekly (2009-08-04)
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