Gastrointestinal Stromal Tumors

Reports from Y. Suehara et al highlight recent research in gastrointestinal stromal tumors

Published in Cancer Weekly, August 4th, 2009

According to a study from Tsukiji, Japan, "The gastrointestinal stromal tumor (GIST) is the most common mesenchymal malignancy of the gastrointestinal tract. Its clinical course ranges widely from a curable disorder to a highly malignant disease."

"Although its clinical and molecular characteristics depend on the anatomic site of origin, the molecular background of GIST arising in different anatomical site has not been studied yet. To investigate the proteomic background of GIST, we examined the proteomic features corresponding to the anatomic site of tumor origin. Comparison of the proteomic profile of gastric (23 cases) and small intestinal (9 cases) GIST by 2-DE...

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Source: Cancer Weekly (2009-08-04)

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