Germ Cell Cancer

Scientists at University Hospital discuss research in germ cell cancer

Published in Cancer Weekly, August 4th, 2009

According to a study from Nice, France, "Fetal exposure to environmental estrogens may contribute to hypofertility and/or to testicular germ cell cancer. However, many of these xenoestrogens have only a weak affinity for the classical estrogen receptors (ERs,) which is 1,000-fold less potent than the affinity of 17 beta-estradiol (E-2)."

"Thus, several mechanisms have been suggested to explain how they could affect male germ cell proliferation at low environmental relevant concentrations. In this study we aimed to explore the possible promoting effect of bisphenol A (BPA) on human testicullar seminoma cells. BPA is a well-recognized estrogenic endocrine disruptor used...

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Source: Cancer Weekly (2009-08-04)

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