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Studies from University of Colorado reveal new findings on life sciences

Published in Cancer Weekly, August 4th, 2009

According to a study from the United States, "Eribulin mesylate (E7389) is a synthetic analog of the marine macrolide halichondrin B, which acts as a novel microtubule modulator with a distinct mechanism of action."

"Two eribulin mesylate phase 1 studies exploring weekly and 3-weekly schedules are reported in this issue. These trials show linear pharmacokinetics, a toxicity profile consisting in neutropenia and fatigue, and early hints of antitumor activity," wrote A. Jimeno and colleagues, University of Colorado.

The researchers concluded: "In this commentary we give a brief historical perspective of the halichondrins and put into context eribulin...

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