Lung Cancer

Data on lung cancer published by researchers at Yale University, Medical Department

Published in Cancer Weekly, August 4th, 2009

According to recent research published in the journal Clinical Cancer Research, "Mammalian target of rapamycin (mTOR) is a key kinase downstream of phosphoinositide 3-kinase (PI3K)/AKT predominantly involved in translational control in the presence of nutrients and energy. Despite the well known role of mTOR in carcinogenesis, its prognostic potential in lung cancer has not been investigated."

"Here, we quantitatively assessed mTOR protein expression in two large data sets to investigate the impact of mTOR expression on patient survival. Automated quantitative analysis (AQUA), a fluorescent-based method for analysis of in situ protein expression, was used to...

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Source: Cancer Weekly (2009-08-04)

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