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Physiology

Research on physiology discussed by R. Sartori and co-researchers

Published in Cancer Weekly, August 4th, 2009

According to a study from Padua, Italy, "Sartori R, Milan G, Patron M, Mammucari C, Blaauw B, Abraham R, Sandri M. Smad2 and 3 transcription factors control muscle mass in adulthood. Am J Physiol Cell Physiol 296: C1248-C1257, 2009."

"First published April 8, 2009; doi:10.1152/ajpcell.00104.2009. -Loss of muscle mass occurs in a variety of diseases, including cancer, chronic heart failure, aquired immunodeficiency syndrome, diabetes, and renal failure, often aggravating pathological progression. Preventing muscle wasting by promoting muscle growth has been proposed as a possible therapeutic approach. Myostatin is an important negative modulator of muscle growth during...

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