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Squamous Cell Carcinoma Prognosis

New squamous cell carcinoma prognosis research from Norwegian Radium Hospital, Division of Pathology described

Published in Cancer Weekly, August 4th, 2009

Fresh data on squamous cell carcinoma are presented in the report 'Expression of 14-3-3sigma in cervical squamous cell carcinomas: relationship with clinical outcome.' According to recent research published in the journal Oncology Reports, "14-3-3 sigma (sigma) sequesters the cdc2-cyclin B1 complex in the cytoplasm resulting in G2 arrest. Inactivation and reduced expression of 14-3-3sigma have been reported in a varity of cancers."

"In the present study, we investigated the expression of 14-3-3sigma in a series of 297 cervical squamous cell carcinoma (SCC) to clarify the prognostic value. Using immunohistochemical methods we found high levels of 14-3-3sigma...

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