Breast Cancer
New research on breast cancer from Y. Zhang and co-authors summarized
Published in Cancer Weekly, August 4th, 2009
In this recently published article, scientists in Rotterdam, Netherlands conducted a study "To assess the benefit from adjuvant systemic tamoxifen therapy in breast cancer risk groups identified by the previously established prognostic 76-gene signature. In 300 lymph node-negative (LNN), estrogen receptor-positive (ER+) breast cancer patients (136 treated with adjuvant tamoxifen, 164 having received no systemic adjuvant therapy), distant metastasis-free survival (DMFS) as a function of the 76-gene signature was determined in a multicenter fashion."
"In 136 tamoxifen-treated patients, the 76-gene signature identified a group of patients with a poor prognosis [hazard...
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Source: Cancer Weekly (2009-08-04)
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