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Cancer Vaccines

New cancer vaccines study findings reported from Cleveland Clinic

Published in Cancer Weekly, August 11th, 2009

According to recent research published in the journal Investigational New Drugs, "TG4010 is a recombinant MVA vector expressing the tumor-associated antigen MUC1 and IL2. We explored the effect two schedules of TG4010 on PSA in men with PSA progression."

"A randomized phase II trial was conducted in 40 patients with PSA progression. had PSA doubling times less than 10 months, with no overt evidence of disease. received either weekly subcutaneous injection (sc) of TG4010 10(8) pfu for 6 weeks, then one injection every 3 weeks or sc injection of TG4010 10(8) pfu every 3 weeks. The primary endpoint of a 50% decrease in PSA values from baseline was not observed....

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