Colon Cancer
Findings from M. Panczyk and co-authors provide new insights into colon cancer
Published in Cancer Weekly, August 11th, 2009
"The aim of this study was to determine the significance of three most common single-nucleotide polymorphisms (SNPs) of ABCB1 gene in the development of colorectal cancer and to estimate the influence of these SNPs to surviving patients' treatment combination adjuvant therapy 5-fluorouracil/leucovorin. Haplotype structure of ABCB1 was analysed, and degree of linkage disequilibrium (LD) between SNPs of ABCB1 was estimated," scientists writing in the International Journal of Colorectal Disease report.
"Tumour specimens of 95 patients with colorectal cancer and blood samples of 95 healthy cases were studied. Genotyping of ABCB1 gene was performed by automated...
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Source: Cancer Weekly (2009-08-11)
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