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Ectopic ACTH Syndrome

Data on ectopic ACTH syndrome reported by S.M. Corsello and co-researchers

Published in Cancer Weekly, August 11th, 2009

"Cushing syndrome (CS) is certainly one of the most challenging endocrine disorders. The greatest problem involves the differentiation between Cushing disease and ectopic ACTH syndrome," scientists in Rome, Italy report.

"We report a patient with ACTH-dependent CS who elsewhere underwent unsuccessful transsphenoidal surgery for a pituitary microadenoma. In our institution, high resolution CT didn't show any chest tumor but laboratory data were consistent with ectopic ACTH secretion. Only In-111 Octreoscan, integrated with SPECT-CT and virtual bronchoscopy, allowed the diagnosis of ectopic Cushing syndrome due to occult bronchial carcinoid," wrote S.M. Corsello and...

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