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Research conducted at A.L. Salmela and co-authors has provided new information about life sciences

Published in Cancer Weekly, August 11th, 2009

"Fisetin is a natural flavonol present in edible vegetables, fruits and wine at 2-160 mu g/g concentrations and an ingredient in nutritional supplements with much higher concentrations. The compound has been reported to exert anticarcinogenic effects as well as antioxidant and anti-inflammatory activity via its ability to act as an inhibitor of cell proliferation and free radical scavenger, respectively," investigators in Turku, Finland report.

"Our cell-based high-throughput screen for small molecules that override chemically induced mitotic arrest identified fisetin as an antimitotic compound. Fisetin rapidly compromised microtubule drug-induced mitotic block in a...

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