Ludwig Institute for Cancer Research
Could therapeutic vaccines treat hard to beat breast cancers?
Published in Cancer Weekly, August 11th, 2009
A comprehensive analysis of nearly 1,600 tumor samples has found that CT-X genes are expressed in nearly half the breast cancers that lack the estrogen receptor (ER). CT-X gene products are the targets of therapeutic cancer vaccines already in phase III clinical trials for lung cancer and melanoma. The study-to be published in the Early Edition of the Proceedings of the National Academy of Sciences this week-was led by the international Ludwig Institute for Cancer Research (LICR).
ER negative breast cancers, which account for a third of all breast cancer cases, are a group of tumors that has a generally poor prognosis and few therapy options. A subgroup of the ER...
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Source: Cancer Weekly (2009-08-11)
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