Non-Small Cell Lung Cancer

Reports from M.L. Sos et al highlight recent research in non-small cell lung cancer

Published in Cancer Weekly, August 11th, 2009

"Somatic genetic alterations in cancers have been linked with response to targeted therapeutics by creation of specific dependency on activated oncogenic signaling pathways. However, no tools currently exist to systematically connect such genetic lesions to therapeutic vulnerability," scientists in Cologne, Germany report.

"We have therefore developed a genomics approach to identify lesions associated with therapeutically relevant oncogene dependency. Using integrated genomic profiling, we have demonstrated that the genomes of a large panel of human non-small cell lung cancer (NSCLC) cell lines are highly representative of those of primary NSCLC tumors. Using cell-based...

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Source: Cancer Weekly (2009-08-11)

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