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Breast Cancer Immunology

Studies from Harvard University, Dana-Farber Cancer Institute in the area of breast cancer immunology published

Published in Cancer Weekly, August 11th, 2009

Current study results from the report, 'Identification of CD44v6(+)/CD24- breast carcinoma cells in primary human tumors by quantum dot-conjugated antibodies,' have been published. "Breast carcinoma cells with the CD44+/CD24(low) phenotype have been reported to exhibit 'cancer stem cell' (CSC) characteristics on the basis of their enhanced tumorigenicity and self-renewal potential in immunodeficient mice. We used immunohistochemistry to study the expression of these proteins in whole tissue sections of human breast carcinoma," investigators in the United States report.

"We found that the fraction of CD44v6+ cells is higher in estrogen receptor-positive carcinomas after...

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