Cancer Gene Therapy
New cancer gene therapy study findings have been published by scientists at Northeastern University
Published in Cancer Weekly, August 11th, 2009
"The treatment of cancer using macromolecular therapeutics such as oligonucleotides or peptides requires efficient delivery systems capable of intracellular penetration and may also benefit from use of a combination of therapeutics with different mechanisms of action. With this possibility in mind, we constructed cationic liposome loaded with the proapoptotic peptide, D-(KLAKLAK)(2) and the Bcl-2 antisense oligodeoxynucleotide, G3139, and determined whether the combination of the proapoptotic macromolecules in a single cationic liposome can enhance antitumor efficacy," researchers in the United States report.
"Advantage was taken of alternating charge interaction to...
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Source: Cancer Weekly (2009-08-11)
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