Squamous Cell Carcinoma
Reports outline squamous cell carcinoma study results from University of Hong Kong, Department of Clinical Oncology
Published in Cancer Weekly, August 18th, 2009
Investigators publish new data in the report 'Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma.' "Deletion of 3p is one of the most frequent genetic alterations in many tumors, including esophageal squamous cell carcinoma (ESCC). In our recent study, deletion of 3p24 was frequently detected in ESCC and one candidate tumor suppressor gene (TSG), p300/CBP-associated factor (PCAF), was identified within the region," scientists writing in the journal Oncogene report.
"In this study, downregulation of PCAF was detected in 23/40 (57.5%) of primary ESCCs and 4/9 (44.4%)...
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Source: Cancer Weekly (2009-08-18)
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