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Cancer Vaccines

Data on cancer vaccines detailed by researchers at University of Maryland

Published in Cancer Weekly, August 25th, 2009

"We conducted a clinical trial of peptide prostate specific antigen (PSA): 154-163 (155L) vaccination in human leukocyte antigen (HLA)-A2 patients with detectable and rising serum PSA after radical prostatectomy for prostate cancer (Clinicaltrials.gov identifier NCT00109811). The trial was a single dose-level, phase 2 pilot trial of 1 mg of PSA: 154-163 (155L) emulsified with adjuvant (Montanide ISA-51)," scientists writing in the Journal of Immunotherapy report.

"The primary end-point was the determination of immunogenicity of the vaccine; secondary outcomes were determination of toxicity and effect oil serum PSA. The vaccine was given Subcutaneously 7 times oil...

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