Prostate Cancer
Reports outline prostate cancer study results from P. Fuzio et al
Published in Cancer Weekly, August 25th, 2009
"The beta 1C integrin is an alternatively spliced variant of the beta 1 integrin subfamily that at variance with its wildtype counterpart, i.e., the beta 1A integrin, inhibits cell proliferation in prostate cancer cells. We have recently shown that transcriptional, translational and post-translational processes contribute to the selective loss of beta 1C integrin during prostate malignant transformation," researchers in Bari, Italy report.
"Here, we investigated whether androgen deprivation therapy (ADT) may affect beta 1C mRNA expression in prostate cancer. Neoplastic prostates were obtained from patients undergoing radical prostatectomy who had received neoadjuvant...
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Source: Cancer Weekly (2009-08-25)
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