Vascular Endothelial Growth Factor
Reports on vascular endothelial growth factor findings from M. Yanagisawa and co-researchers provide new insights
Published in Cancer Weekly, August 25th, 2009
According to recent research from Kanagawa, Japan, "To understand the mechanisms of the effects of combination treatments, we established animal models showing antitumor activity of bevacizumab as a monotherapy and in combination with capecitabine or capecitabine and oxaliplatin and measured thymidine phosphorylase (TP) and vascular endothelial growth factor (VEGF) levels. Tumor-inoculated nude mice were treated with bevacizumab, capecitabine, and oxaliplatin, alone or in combination, after tumor growth was confirmed and volume and microvessel density (MVD) in tumors were evaluated."
"Levels of TP and VEGF in the tumor were examined by ELISA. Bevacizumab showed...
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Source: Cancer Weekly (2009-08-25)
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