Breast Cancer

Data from M.C.W. Gast et al provide new insights into breast cancer

Published in Cancer Weekly, September 15th, 2009

According to recent research from Netherlands, "Issues have been raised concerning the robustness and validity of alleged serum markers discovered by surface-enhanced laser desorption/ionisation time-of-flight mass spectrometry (SELDI-TOF MS). Pre-analytical variables have been shown to exert a profound effect on protein profiles, irrespective of true biological variation."

"However, little is known about the possible effects of sample storage duration on protein profiles. We, therefore, aimed to investigate the effects of extended storage duration on the serum protein profile. Archival sera from 140 breast cancer patients, stored at -30 degrees C for 1-11 years, were...

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Source: Cancer Weekly (2009-09-15)

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