Published in Cancer Weekly, September 29th, 2009
"The purpose of this study was to investigate the relationship between KRAS and BRAF mutations in 24 CRC cell lines and 29 advanced CRCs. KRAS and BRAF mutations were detected using high resolution melting and sequencing. Expression of mutations was confirmed by reverse transcription-PCR (RT-PCR) and sequencing. CpG island methylator phenotype (CIMP) was tested by...
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