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Cervical Intraepithelial Neoplasia

Studies from A.B. Abdul et al further understanding of cervical intraepithelial neoplasia

Published in Cancer Weekly, October 6th, 2009

"Recent in vitro and in vivo studies have demonstrated that zerumbone (ZER) possesses anticancer properties. The main objective of this study was to examine the effectiveness of the combination of ZER and cisplatin (CIS) to treat cervical intraepithelial neoplasia (CIN) in vivo," scientists writing in the International Journal of Gynecological Cancer report.

"Microculture tetrazolium assay and immunohistochemistry of proliferating cellular nuclear antigen were used to study the antitumor effect of ZER. Prenatally exposed female BALB/c mice were used as a model. The progenies with CIN were injected peritoneally with isotonic sodium chloride solution (positive...

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