Sarcoma
Reports summarize sarcoma research from Mayo Clinic
Published in Cancer Weekly, October 20th, 2009
"The entry process of the avian sarcoma and leukosis virus (ASLV) family of retroviruses requires first a specific interaction between the viral surface (SU) glycoproteins and a receptor on the cell surface at a neutral pH, triggering conformational changes in the viral SU and transmembrane ™ glycoproteins, followed by exposure to low pH to complete fusion. The ASLV TM glycoprotein has been proposed to adopt a structure similar to that of the Ebola virus GP2 protein: each contains an internal fusion peptide flanked by cysteine residues predicted to be in a disulfide bond," scientists writing in the Journal of Virology report.
"In a previous study, we...
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Source: Cancer Weekly (2009-10-20)
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