Breast Cancer

Reports summarize breast cancer research from R.U. Kusinska and co-authors

Published in Cancer Weekly, October 27th, 2009

"Vimentin is one of the cytoplasmic intermediate filament proteins which are the major component of the cytoskeleton. In our study we checked the usefulness of vimentin expression in identifying cases of breast cancer with poorer prognosis, by adding vimentin to the immunopanel consisting of basal type cytokeratins, estrogen, progesterone, and HER2 receptors," scientists in Lodz, Poland report.

"179 tissue specimens of invasive operable ductal breast cancer were assessed by the use of immunohistochemistry. The median follow-up period for censored cases was 90 months. 38 cases (21.2%) were identified as being vimentin-positive. Vimentin-positive tumours affected younger...

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Source: Cancer Weekly (2009-10-27)

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