Cancer Gene Therapy

New cancer gene therapy research from V. Mlakar and colleagues discussed

Published in Cancer Weekly, November 10th, 2009

According to a study from Ljubljana, Slovenia, "Electroporation is a versatile method for in vitro or in vivo delivery of different molecules into cells. However, no study so far has analysed the effects of electric pulses used in electrochemotherapy (ECT pulses) or electric pulses used in electrogene therapy (EGT pulses) on malignant cells."

"We studied the effect of ECT and EGT pulses on human malignant melanoma cells in vitro in order to understand and predict the possible effect of electric pulses on gene expression and their possible effect on cell behaviour. We used microarrays with 2698 different oligonucleotides to obtain the expression profile of genes involved...

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Source: Cancer Weekly (2009-11-10)

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