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RNA Research

Scientists at Genome Sciences Center publish research in RNA research

Published in Cancer Weekly, November 17th, 2009

A report, 'De novo transcriptome assembly with ABySS,' is newly published data in Bioinformatics. "Whole transcriptome shotgun sequencing data from non-normalized samples offer unique opportunities to study the metabolic states of organisms. One can deduce gene expression levels using sequence coverage as a surrogate, identify coding changes or discover novel isoforms or transcripts," scientists in Vancouver, Canada report.

"Especially for discovery of novel events, de novo assembly of transcriptomes is desirable. Transcriptome from tumor tissue of a patient with follicular lymphoma was sequenced with 36 base pair (bp) single-and paired-end reads on the Illumina...

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