Angiogenesis
New angiogenesis study results from M. Yi et al described
Published in Cancer Weekly, November 17th, 2009
According to recent research published in the journal Proceedings of the National Academy of Sciences of the United States of America, "Despite 2 decades of research, no clear function for annexin A1 (AnxA1) has been established. Using AnxA1-KO mice, we show that tumor growth and metastasis are significantly decreased, whereas rodent survival and tumor necrosis are greatly increased when tumors grow in AnxA1-KO mice."
"Systems analysis of gene expression in these tumors specifically implicates 2 related vascular functions, angiogenesis and wound healing, in this impairment. Both tumor vascular development and wound healing are greatly retarded in KO tissues....
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Source: Cancer Weekly (2009-11-17)
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