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Breast Cancer

Research on breast cancer detailed by scientists at University of Turku, Center for Biotechnology

Published in Cancer Weekly, December 1st, 2009

New investigation results, 'Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines,' are detailed in a study published in Oncogene. "Predicting the impact of microRNAs (miRNAs) on target proteins is challenging because of their different regulatory effects at the transcriptional and translational levels. In this study, we applied a novel protein lysate microarray (LMA) technology to systematically monitor for target protein levels after high-throughput transfections of 319 pre-miRs into breast cancer cells," scientists writing in the journal Oncogene report.

"We identified 21 miRNAs that...

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