Phyllodes Tumors

Data on phyllodes tumors published by researchers at Royal Prince Alfred Hospital

Published in Cancer Weekly, December 8th, 2009

"The Wnt pathway is important in cell signalling transduction and is involved in the pathogenesis of multiple tumour types. A comprehensive analysis of the expression of Wnt signalling pathway proteins in mammary phyllodes tumours (PTs) has not been previously performed," investigators in Camperdown, Australia report.

"To evaluate the immunohistochemical expression of Wnt pathway proteins in a cohort of PTs, to determine their role in tumour pathogenesis and to identify any associations with patient outcome. 65 PTs (34 benign, 23 borderline and 8 malignant) diagnosed at a single institution between 1990 and 2006 were analysed. Immunohistochemical stains were performed...

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Source: Cancer Weekly (2009-12-08)

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