Apoptosis
Studies from University of Teramo reveal new findings on apoptosis
Published in Cancer Weekly, December 8th, 2009
According to a study from Teramo, Italy, "Anandamide (AEA) is an endogenous agonist of type 1 cannabinoid receptors (CB1R) that, along with metabolic enzymes of AEA and congeners, compose the ''endocannabinoid system.'' Here we report the biochemical, morphological, and functional characterization of the endocannabinoid system in human neuroblastoma SH-SY5Y cells that are an experimental model for neuronal cell damage and death, as well as for major human neurodegenerative disorders. We also show that AEA dose-dependently induced apoptosis of SH-SY5Y cells."
"Through proteomic analysis, we further demonstrate that AEA-induced apoptosis was paralleled by an similar to 3...
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Source: Cancer Weekly (2009-12-08)
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