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Journal of the National Cancer Institute

Higher risk for heart disease and diabetes associated with androgen deprivation therapy

Published in Cancer Weekly, December 22nd, 2009

Men of all ages treated for prostate cancer with androgen deprivation therapy, specifically with gonadotropin-releasing hormone agonists (GnRH), have an increased risk of diabetes and cardiovascular disease, according to a new study published online December 7 in the Journal of the National Cancer Institute.

Previous studies indicate that older men who take androgen deprivation therapy for prostate cancer are at an increased risk for diabetes and cardiovascular disease, but the relationship between the two among men of all ages is unclear.

Nancy L. Keating, M.D., MPH, of the Division of General Internal Medicine, Department of Medicine, Brigham and...

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